Blue Rubber Bleb Nevus (BRBN)

Blue Rubber Bleb Nevus, also known as bean syndrome, is related to venous malformations, multiple cutaneous and mucosal and glomuvenous malformations. An important gene associated with Blue Rubber Bleb Nevus is GLMN (Glomulin, FKBP Associated Protein). The drugs Temsirolimus and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotypes are arteriovenous malformation and skin rash