Blind Loop Syndrome, also known as bacterial overgrowth syndrome, is related to megaesophagus and duodenal obstruction. An important gene associated with Blind Loop Syndrome is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways is Cobalamin (Cbl, vitamin B12) transport and metabolism. The drugs Rifaximin and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include small intestine and liver, and related phenotypes are homeostasis/metabolism and growth/size/body region