Bulimia Nervosa, also known as bulimia, is related to abdominal obesity-metabolic syndrome 1 and polysubstance abuse, and has symptoms including salt craving and decrease in appetite. An important gene associated with Bulimia Nervosa is BULN (Bulimia Nervosa, Susceptibility To), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Orlistat and Sibutramine have been mentioned in the context of this disorder. Affiliated tissues include prefrontal cortex and brain, and related phenotypes are bulimia and nervous system