Bladder Dysfunction, Autonomic, with Impaired Pupillary Reflex and Secondary Cakut, is also known as urinary bladder, atony of. An important gene associated with Bladder Dysfunction, Autonomic, with Impaired Pupillary Reflex and Secondary Cakut is CHRNA3 (Cholinergic Receptor Nicotinic Alpha 3 Subunit). Affiliated tissues include kidney, and related phenotypes are slow pupillary light response and vesicoureteral reflux