Body Mass Index Quantitative Trait Locus 11 (BMIQ11)

Body Mass Index Quantitative Trait Locus 11(来自ICD-11)
别称:
Obesity
Leanness, Inherited
Obesity, Early-Onset, Susceptibility to
Obesity, Severe, and Type Ii Diabetes
Obesity, Susceptibility to, Bmiq11
Obesity , Susceptibility to
Obesity, Susceptibility to
Obesity, Mild, Early-Onset
Obesity, Association with
Obesity, Late-Onset
Obesity, Severe
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified
Obesity, Early-Onset
Simple Obesity Nos
Inherited Obesity
Obesity Bmiq11
Excess Fat
Adiposis
Bmiq11
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Body Mass Index Quantitative Trait Locus 11, also known as obesity, is related to leptin deficiency or dysfunction and type 2 diabetes mellitus, and has symptoms including high weight, obesity, metabolically benign and monogenic obesity. An important gene associated with Body Mass Index Quantitative Trait Locus 11 is PPARG (Peroxisome Proliferator Activated Receptor Gamma), and among its related pathways/superpathways are Glucose / Energy Metabolism and Development Ligand-independent activation of ESR1 and ESR2. The drugs Metyrapone and Indapamide have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and liver, and related phenotypes are obesity and decreased resting energy expenditure
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相关ID:
MESH:D009765
ICD11:149403041

基础信息

遗传方式
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参考文献
MALACARDS
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