B Cell Deficiency, also known as immunoglobulin heavy chain deficiency, is related to agammaglobulinemia and selective immunoglobulin deficiency disease. An important gene associated with B Cell Deficiency is BTK (Bruton Tyrosine Kinase), and among its related pathways/superpathways are ERK Signaling and Innate Immune System. The drugs Adjuvants, Immunologic and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include b cells and bone marrow, and related phenotypes are homeostasis/metabolism and nervous system