Atypical Chronic Myeloid Leukemia, Bcr-Abl1 Negative (ACML)

Atypical Chronic Myeloid Leukemia, Bcr-Abl1 Negative, also known as leukemia, myeloid, chronic, atypical, bcr-abl negative, is related to leukemia, chronic myeloid and myeloid leukemia. An important gene associated with Atypical Chronic Myeloid Leukemia, Bcr-Abl1 Negative is ASXL1 (ASXL Transcriptional Regulator 1), and among its related pathways/superpathways are RAF/MAP kinase cascade and Actin Nucleation by ARP-WASP Complex. The drugs Ondansetron and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are Decreased viability and Decreased substrate adherent cell growth