Autosomal Dominant Intellectual Developmental Disorder 19 (MRD19)

Autosomal Dominant Intellectual Developmental Disorder 19, also known as autosomal dominant non-syndromic intellectual disability 19, is related to neurodevelopmental disorder with spastic diplegia and visual defects and childhood kidney cell carcinoma. An important gene associated with Autosomal Dominant Intellectual Developmental Disorder 19 is SGPL1 (Sphingosine-1-Phosphate Lyase 1), and among its related pathways/superpathways are Infectious disease and Metabolism of proteins. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased mitotic index