Autosomal Dominant Severe Congenital Neutropenia

Autosomal Dominant Severe Congenital Neutropenia is related to severe congenital neutropenia 8 and severe congenital neutropenia 2. An important gene associated with Autosomal Dominant Severe Congenital Neutropenia is GFI1 (Growth Factor Independent 1 Transcriptional Repressor), and among its related pathways/superpathways are Phase 0 - rapid depolarisation and Interaction between L1 and Ankyrins. Affiliated tissues include neutrophil and myeloid, and related phenotypes are neutropenia and recurrent bacterial infections