Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Alias:
Polycystic Kidney, Autosomal Dominant
Adpkd
Polycystic Kidney Diseases
Kidney, Polycystic, Disease, Autosomal Dominant
Polycystic Kidney Disease, Autosomal Dominant
Apckd - [autosomal Polycystic Kidney Disease]
Polycystic Kidney and Hepatic Disease 1
Adult Polycystic Kidney Disease
Polycystic Kidney, Adult Type
Congenital Biliary Ectasias
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Autosomal Dominant Polycystic Kidney Disease, also known as polycystic kidney, autosomal dominant, is related to polycystic kidney disease 1 with or without polycystic liver disease and polycystic kidney disease. An important gene associated with Autosomal Dominant Polycystic Kidney Disease is PKD2 (Polycystin 2, Transient Receptor Potential Cation Channel), and among its related pathways/superpathways are Bardet-Biedl syndrome and Ciliopathies. The drugs Angiotensin II and Candesartan cilexetil have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver, and related phenotypes are renal insufficiency and renal cyst
Related ID:
MESH:D007690
ICD11:91220434

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Child
1-5/10000
132
1202
293

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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