Atrial Standstill 1 (ATRST1)

Atrial Standstill 1, also known as cardiomyopathy, familial, with conduction disturbance, is related to atrial standstill and progressive familial heart block, type ia, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Atrial Standstill 1 is GJA5 (Gap Junction Protein Alpha 5), and among its related pathways/superpathways are DREAM Repression and Dynorphin Expression and Antiarrhythmic Pathway, Pharmacodynamics. The drugs Dolutegravir and Abacavir have been mentioned in the context of this disorder. Affiliated tissues include heart and bone marrow, and related phenotypes are ventricular escape rhythm and paroxysmal atrial fibrillation