Atrial Fibrillation, Familial, 10, also known as atfb10, is related to sick sinus syndrome 1 and progressive familial heart block, type ia. An important gene associated with Atrial Fibrillation, Familial, 10 is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5). Affiliated tissues include heart and heart-atrium, and related phenotypes are tricuspid regurgitation and bradycardia