Autoinflammation with Infantile Enterocolitis (AIFEC)

Autoinflammation with Infantile Enterocolitis, also known as periodic fever-infantile enterocolitis-autoinflammatory syndrome, is related to enterocolitis and familial cold autoinflammatory syndrome 4, and has symptoms including arthralgia, exanthema and myalgia. An important gene associated with Autoinflammation with Infantile Enterocolitis is NLRC4 (NLR Family CARD Domain Containing 4). The drugs Ceftriaxone and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and skin, and related phenotypes are failure to thrive and splenomegaly