Autoimmune Lymphoproliferative Syndrome (ALPS)

Alias:

Alps

Canale-Smith Syndrome

Autoimmune Lymphoproliferative Syndrome, Type Ia

Autoimmune Lymphoproliferative Syndrome, Type Ib

Autoimmune Lymphoproliferative Syndrome, Type 1b

Autoimmune Lymphoproliferative Syndrome, Type 1a

Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant

Autoimmune Lymphoproliferative Syndrome Type Ia

Autoimmune Lymphoproliferative Syndrome Type Ib

Autoimmune Lymphoproliferative Syndrome Type 1

Autoimmune Lymphoproliferative Syndrome 1a

Autoimmune Lymphoproliferative Syndrome 1b

Alps1a

Alps1b

Css

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Autoimmune Lymphoproliferative Syndrome, also known as alps, is related to caspase 8 deficiency and ras-associated autoimmune leukoproliferative disorder. An important gene associated with Autoimmune Lymphoproliferative Syndrome is FASLG (Fas Ligand), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Amlodipine and Vasodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include spleen and liver, and related phenotypes are splenomegaly and autoimmunity

Related ID：

MALACARDS：ATM006

OMIM：601859

MESH：D056735