Aortic Valve Disease 3 (AOVD3)

Aortic Valve Disease 3, also known as bicuspid aortic valve, is related to aortic valve disease 2 and patent ductus arteriosus and bicuspid aortic valve with hand anomalies. An important gene associated with Aortic Valve Disease 3 is ROBO4 (Roundabout Guidance Receptor 4). The drugs Propofol and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include heart and endothelial, and related phenotypes are aortic root aneurysm and bicuspid aortic valve