Aortic Aneurysm, Familial Thoracic 6 (AAT6)

Aortic Aneurysm, Familial Thoracic 6, also known as familial thoracic aortic aneurysm with livedo reticularis and iris flocculi, is related to sleeping sickness and trypanosomiasis. An important gene associated with Aortic Aneurysm, Familial Thoracic 6 is ACTA2 (Actin Alpha 2, Smooth Muscle). Affiliated tissues include smooth muscle and skin, and related phenotypes are ascending aortic dissection and premature coronary artery atherosclerosis