Arthrogryposis, Renal Dysfunction, and Cholestasis 2 (ARCS2)

Arthrogryposis, Renal Dysfunction, and Cholestasis 2, also known as arcs2, is related to arthrogryposis, renal dysfunction, and cholestasis 1 and cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome, and has symptoms including icterus An important gene associated with Arthrogryposis, Renal Dysfunction, and Cholestasis 2 is VIPAS39 (VPS33B Interacting Protein, Apical-Basolateral Polarity Regulator, Spe-39 Homolog), and among its related pathways/superpathways are Deubiquitination and NAD metabolism. Affiliated tissues include liver and kidney, and related phenotypes are nephrogenic diabetes insipidus and lissencephaly