Aortic Valve Prolapse is related to aortic valve insufficiency and ventricular septal defect. An important gene associated with Aortic Valve Prolapse is CCDC33 (Coiled-Coil Domain Containing 33), and among its related pathways/superpathways are Small cell lung cancer and Binding and Uptake of Ligands by Scavenger Receptors. Affiliated tissues include heart.