Argininosuccinic Aciduria (ARGINSA)

Argininosuccinic Aciduria, also known as argininosuccinate lyase deficiency, is related to carbamoyl phosphate synthetase i deficiency, hyperammonemia due to and ornithine transcarbamylase deficiency, hyperammonemia due to, and has symptoms including ataxia, lethargy and seizures. An important gene associated with Argininosuccinic Aciduria is ASL (Argininosuccinate Lyase), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. The drugs Carbamide peroxide and Nitric Oxide have been mentioned in the context of this disorder. Affiliated tissues include liver and skin, and related phenotypes are aminoaciduria and oroticaciduria