Arcus Corneae, also known as arcus senilis, is related to arteries, anomalies of and peripheral artery disease. An important gene associated with Arcus Corneae is APOB (Apolipoprotein B), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Nuclear receptors meta-pathway. Affiliated tissues include heart and eye, and related phenotypes are Increased free cholesterol and Increased LDL uptake