Aplasia of Lacrimal and Salivary Glands (ALSG)

Alias:
Alsg
Congenital Absence of Lacrimal Puncta and Salivary Glands
Xerostomia
Congenital Absence of Lacrimal Puncta or Salivary Glands
Alsg - [aplasia of Lacrimal or Salivary Glands]
Congenital Absence of Salivary Gland
Parotid Aplasia or Hypoplasia
Absence of Salivary Glands
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Aplasia of Lacrimal and Salivary Glands, also known as alsg, is related to xerophthalmia and sialadenitis, and has symptoms including halitosis, signs and symptoms, digestive and snoring. An important gene associated with Aplasia of Lacrimal and Salivary Glands is FGF10 (Fibroblast Growth Factor 10), and among its related pathways/superpathways are Development FGFR signaling pathway and Regulation of actin cytoskeleton. The drugs Cevimeline and Sodium fluoride have been mentioned in the context of this disorder. Affiliated tissues include salivary gland and eye, and related phenotypes are carious teeth and xerostomia
Related ID:
MESH:C562407
ICD11:1810717437

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
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13
161
13

Medical Symptom

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Description
HPO Frequency
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HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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No data available

Disease Model

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MGI
Related Gene
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Publications
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References Literature

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