Antithrombin Iii Deficiency (AT3D)

Antithrombin Iii Deficiency, also known as hereditary antithrombin deficiency, is related to budd-chiari syndrome and nephrotic syndrome. An important gene associated with Antithrombin Iii Deficiency is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. The drugs Heparin, bovine and Calcium heparin have been mentioned in the context of this disorder. Affiliated tissues include bone and liver, and related phenotypes are reduced antithrombin iii activity and reduced antithrombin antigen