Annular Erythema, also known as erythema annulare, is related to keratolytic winter erythema and neonatal lupus erythematosus. An important gene associated with Annular Erythema is CTSB (Cathepsin B), and among its related pathways/superpathways is Extracellular matrix organization. Affiliated tissues include skin and breast, and related phenotype is erythema.