Amyloidosis, Primary Localized Cutaneous, 3 (PLCA3)

Amyloidosis, Primary Localized Cutaneous, 3, also known as amyloidosis cutis dyschromica, is related to amyloidosis and primary cutaneous amyloidosis. An important gene associated with Amyloidosis, Primary Localized Cutaneous, 3 is GPNMB (Glycoprotein Nmb), and among its related pathways/superpathways is Interleukin-6 family signaling. Affiliated tissues include skin and colon, and related phenotypes are dry skin and generalized hyperpigmentation