Amyotrophic Lateral Sclerosis 8, also known as amyotrophic lateral sclerosis type 8, is related to spinal muscular atrophy and muscular atrophy, and has symptoms including muscular fasciculation, static tremor and weakness. An important gene associated with Amyotrophic Lateral Sclerosis 8 is VAPB (VAMP Associated Protein B And C). Affiliated tissues include spinal cord and brain, and related phenotypes are postural tremor and fasciculations