Amyotrophic Lateral Sclerosis 4, Juvenile, also known as amyotrophic lateral sclerosis type 4, is related to frontotemporal dementia and/or amyotrophic lateral sclerosis 4 and oculomotor apraxia, and has symptoms including upper motor neuron signs An important gene associated with Amyotrophic Lateral Sclerosis 4, Juvenile is SETX (Senataxin). Affiliated tissues include spinal cord and brain, and related phenotypes are abnormal pyramidal sign and skeletal muscle atrophy