American Histoplasmosis, also known as infection by histoplasma capsulatum, is related to histoplasmosis and epidural abscess. An important gene associated with American Histoplasmosis is HYCC1 (Hyccin PI4KA Lipid Kinase Complex Subunit 1), and among its related pathways/superpathways are a6b1 and a6b4 Integrin signaling and G-protein signaling_Rap2B regulation pathway. Affiliated tissues include tongue, and related phenotype is Increased shRNA abundance (Z-score > 2).