Amenorrhea, also known as absence of menstruation, is related to ovarian dysgenesis 2 and hypogonadotropic hypogonadism 23 with or without anosmia, and has symptoms including ovulation bleeding and menometrorrhagia. An important gene associated with Amenorrhea is FSHR (Follicle Stimulating Hormone Receptor), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Polyestradiol phosphate and Cyproterone acetate have been mentioned in the context of this disorder. Affiliated tissues include pituitary and breast, and related phenotypes are homeostasis/metabolism and nervous system