Alzheimer Disease 2, also known as alzheimer disease associated with apoe4, is related to alzheimer disease 3 and sleep disorder. An important gene associated with Alzheimer Disease 2 is APOE (Apolipoprotein E), and among its related pathways/superpathways are Neuroscience and Apoptosis-related network due to altered Notch3 in ovarian cancer. The drugs Eltanolone and Equol have been mentioned in the context of this disorder. Affiliated tissues include brain and cortex, and related phenotypes are neurofibrillary tangles and dementia