Aleutian Mink Disease, also known as aleutian disease, is related to viral infectious disease and hypersensitivity reaction type iii disease, and has symptoms including weight loss, hepatomegaly and enlarged spleen. An important gene associated with Aleutian Mink Disease is CATSPER4 (Cation Channel Sperm Associated 4), and among its related pathways/superpathways is Fertilization. Affiliated tissues include spleen and kidney.