Alopecia, Congenital, also known as congenital alopecia, is related to t-cell immunodeficiency, congenital alopecia, and nail dystrophy and palmoplantar keratoderma and congenital alopecia 1. An important gene associated with Alopecia, Congenital is HR (HR Lysine Demethylase And Nuclear Receptor Corepressor). Affiliated tissues include salivary gland and skin, and related phenotypes are alopecia and abnormal eyelash morphology