Alopecia Universalis Congenita (ALUNC)

Alopecia Universalis Congenita, also known as alopecia universalis, is related to immunodeficiency 41 with lymphoproliferation and autoimmunity and spondyloarthropathy 1. An important gene associated with Alopecia Universalis Congenita is HR (HR Lysine Demethylase And Nuclear Receptor Corepressor), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Prednisolone and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include skin and thyroid, and related phenotypes are absent eyelashes and absent eyebrow