Alcohol Dependence, also known as alcoholism, is related to alcohol use disorder and personality disorder. An important gene associated with Alcohol Dependence is GABRA2 (Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha2), and among its related pathways/superpathways are Metabolism and Transmission across Chemical Synapses. The drugs Perindopril and Amlodipine have been mentioned in the context of this disorder. Affiliated tissues include liver and brain, and related phenotypes are homeostasis/metabolism and behavior/neurological