Agoraphobia, also known as fear of open spaces, is related to personality disorder and panic disorder. An important gene associated with Agoraphobia is HTR1A (5-Hydroxytryptamine Receptor 1A), and among its related pathways/superpathways are Monoamine transport and Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics. The drugs Escitalopram and Citalopram have been mentioned in the context of this disorder. Affiliated tissues include brain and amygdala, and related phenotypes are Decreased viability and nervous system