Advanced Sleep Phase Syndrome, Familial, 1, also known as advanced sleep phase syndrome 1, is related to advanced sleep phase syndrome, familial, 2 and advanced sleep phase syndrome, familial, 3. An important gene associated with Advanced Sleep Phase Syndrome, Familial, 1 is PER2 (Period Circadian Regulator 2), and among its related pathways/superpathways is Circadian Clock. Affiliated tissues include brain, and related phenotypes are sleep-wake cycle disturbance and depression