Adiposis Dolorosa

Adiposis Dolorosa, also known as dercum disease, is related to body mass index quantitative trait locus 11 and lipomatosis, familial multiple, and has symptoms including arthralgia, constipation and fatigue. An important gene associated with Adiposis Dolorosa is AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2), and among its related pathways/superpathways are Glucose / Energy Metabolism and Adipogenesis. Affiliated tissues include skin and spinal cord, and related phenotypes are depression and fatigue