Acute Myeloid Leukemia with T(1;22)(p13;q13)

Alias:
Acute Myeloid Leukemia (megakaryoblastic) with T(1;22)(p13.3;q13.1); Rbm15-Mkl1
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Acute Myeloid Leukemia with T(1;22)(p13;q13), also known as acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13.3;q13.1); rbm15-mkl1, is related to megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13) and b-lymphoblastic leukemia/lymphoma with tcf3-pbx1. An important gene associated with Acute Myeloid Leukemia with T(1;22)(p13;q13) is NUP214 (Nucleoporin 214), and among its related pathways/superpathways are Signal Transduction and Reelin Pathway (Cajal-Retzius cells). Affiliated tissues include myeloid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and growth/size/body region
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Basic Information

Inheritance
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Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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16
163
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Medical Symptom

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Gene & Mutation

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MGI
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References Literature

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