Acute Myeloid Leukemia with T(8;21); (q22; Q22.1)

Acute Myeloid Leukemia with T(8;21); (q22; Q22.1), also known as acute myeloid leukemia, t(8;21)(q22;q22), is related to mastocytosis and myeloid leukemia. An important gene associated with Acute Myeloid Leukemia with T(8;21); (q22; Q22.1) is RUNX1T1 (RUNX1 Partner Transcriptional Co-Repressor 1), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Fluconazole and Caspofungin have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotype is neoplasm.