Acute Myeloid Leukemia with Minimal Differentiation

Alias:
Minimally Differentiated Acute Myeloblastic Leukemia
Acute Myeloblastic Leukemia, Minimally Differentiated
Acute Myeloid Leukemia, Minimal Differentiation
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Acute Myeloid Leukemia with Minimal Differentiation, also known as minimally differentiated acute myeloblastic leukemia, is related to acute myeloblastic leukemia without maturation and patau syndrome. An important gene associated with Acute Myeloid Leukemia with Minimal Differentiation is FLT3 (Fms Related Receptor Tyrosine Kinase 3), and among its related pathways/superpathways are NF-kappaB Signaling and Tyrosine Kinases / Adaptors. The drugs Fluconazole and Caspofungin have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Adult
<1/1000000
16
330
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Medical Symptom

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Description
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HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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No data available

Disease Model

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MGI
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Publications
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References Literature

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