Acth-Independent Macronodular Adrenal Hyperplasia 2, also known as primary macronodular adrenal hyperplasia, is related to acth-independent macronodular adrenal hyperplasia 1 and acth-independent macronodular adrenal hyperplasia, and has symptoms including agitation and generalized fatigue. An important gene associated with Acth-Independent Macronodular Adrenal Hyperplasia 2 is ARMC5 (Armadillo Repeat Containing 5). The drugs Racepinephrine and Adrenocorticotropic Hormone have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland and kidney, and related phenotypes are increased body weight and abdominal obesity