Acute Graft Versus Host Disease

Acute Graft Versus Host Disease, also known as acute graft-versus-host disease, is related to human cytomegalovirus infection and aplastic anemia. An important gene associated with Acute Graft Versus Host Disease is ARHGAP45 (Rho GTPase Activating Protein 45), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Cytarabine and Lomustine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and bone, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and endocrine/exocrine gland