Acute Myelomonocytic Leukemia (AMMOL)

Acute Myelomonocytic Leukemia, also known as aml m4, is related to acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) and monocytic leukemia. An important gene associated with Acute Myelomonocytic Leukemia is CBFB (Core-Binding Factor Subunit Beta), and among its related pathways/superpathways are NF-kappaB Signaling and Tyrosine Kinases / Adaptors. The drugs Cyclophosphamide and Busulfan have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are anemia and thrombocytopenia