Acute Myeloblastic Leukemia with Maturation

Alias:
Acute Myeloblastic Leukemia M2
Aml M2
Acute Myeloid Leukemia
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Acute Myeloblastic Leukemia with Maturation, also known as acute myeloblastic leukemia m2, is related to acute myeloid leukemia with maturation and myeloid leukemia. An important gene associated with Acute Myeloblastic Leukemia with Maturation is LOC126805969 (BRD4-Independent Group 4 Enhancer GRCh37_chr1:198776880-198778079), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Hippo-Merlin signaling dysregulation. The drugs Nicotine and Amsacrine have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are Decreased substrate adherent cell growth and Increased senescence-associated beta-galactosidase protein expression after pRB stimulation
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
<1/1000000
3
161
1

Medical Symptom

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Gene & Mutation

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MGI
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References Literature

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