Active Peptic Ulcer Disease, also known as gi bleeding, is related to dieulafoy lesion and intestinal tuberculosis, and has symptoms including abdominal pain, chest pain and constipation. An important gene associated with Active Peptic Ulcer Disease is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways are Diseases of hemostasis and Angiogenesis (CST). The drugs Amoxicillin and Prucalopride have been mentioned in the context of this disorder. Affiliated tissues include colon and liver, and related phenotypes are homeostasis/metabolism and growth/size/body region