Acute Closed-Angle Glaucoma, also known as acute angle-closure glaucoma, is related to chronic closed-angle glaucoma and macular degeneration, age-related, 1, and has symptoms including sudden pain An important gene associated with Acute Closed-Angle Glaucoma is TTLL12 (Tubulin Tyrosine Ligase Like 12), and among its related pathways/superpathways are Disulfiram Pathway, Pharmacodynamics (Dopaminergic neuron) and Methylphenidate Pathway, Pharmacodynamics. The drug Sorbitol has been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial, and related phenotype is vision/eye.