Acute Chest Syndrome

Acute Chest Syndrome, also known as acute chest syndrome in sickle cell disease, is related to hereditary persistence of fetal hemoglobin-sickle cell disease syndrome and thalassemia, and has symptoms including fever, pleuritic chest pain and tachypnea. An important gene associated with Acute Chest Syndrome is NOS3 (Nitric Oxide Synthase 3), and among its related pathways/superpathways are Innate Immune System and PI3K-Akt signaling pathway. The drugs Reviparin and Nitric Oxide have been mentioned in the context of this disorder. Affiliated tissues include lung and placenta, and related phenotypes are homeostasis/metabolism and growth/size/body region