2,4-Dienoyl-Coa Reductase Deficiency (DECRD)

2,4-Dienoyl-Coa Reductase Deficiency, also known as progressive encephalopathy with leukodystrophy due to decr deficiency, is related to visceral steatosis, congenital and fatty liver disease 1, and has symptoms including muscle spasticity and seizures. An important gene associated with 2,4-Dienoyl-Coa Reductase Deficiency is NADK2 (NAD Kinase 2, Mitochondrial), and among its related pathways/superpathways is Metabolism. Affiliated tissues include eye and liver, and related phenotypes are seizure and failure to thrive