Rare Disease
Cystic Fibrosis (CF)
Alias:
Mucoviscidosis
Cf
Pseudomonas Aeruginosa, Susceptibility to Chronic Infection by, in Cystic Fibrosis
Pseudomonas Aeruginosa Chronic Infection by, in Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier of
Nonproliferative Fibrocystic Disease
Fibrocystic Disease of the Pancreas
Fibrocystic Disease of Pancreas
Cystic Fibrosis of Pancreas
Mucoviscidosis of Pancreas
Pancreatic Cystic Fibrosis
Cf - [cystic Fibrosis]
Cystic Fibrosis Nos
Fibrocystic Disease
Respiratory diseases
Gastrointestinal diseases
Liver diseases
Reproductive diseases
Basic Information
Cystic Fibrosis, also known as mucoviscidosis, is related to vas deferens, congenital bilateral aplasia of and bronchiectasis with or without elevated sweat chloride 1, and has symptoms including coughing, hemoptysis and snoring. An important gene associated with Cystic Fibrosis is CFTR (CF Transmembrane Conductance Regulator), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. The drugs Ticarcillin and Clavulanic acid have been mentioned in the context of this disorder. Affiliated tissues include Lung and pancreas, and related phenotypes are recurrent respiratory infections and malabsorption
Basic Information
Inheritance
Age Of Onset
Prevalence
Related Gene
Disease Model
Reference
MALACARD
Medical Symptom
Even among those with the same illness, each patient's condition and symptoms are unique. To provide patient-centered medical care, medical professionals must carefully evaluate individual differences between patients. This involves thorough assessment of medical details when diagnosing and developing treatment plans. To achieve personalized and maximally effective care, practitioners refer to the latest research and standards of care to tailor treatment strategies for each patient.
#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
Gene & Mutation
Diseases are frequently associated with anomalies or mutations in certain genes. These genes and mutations can disrupt cellular functioning and induce physiological imbalances, resulting in illnesses. In-depth research on illness genes and mutations can help us better understand disease etiology and give new ideas and approaches for disease prevention, diagnosis, and therapy.
#
Gene
Function
Score
Count
Drugs
Gene target medications are a novel form of treatment that can alter genes or proteins while also blocking disease processes. It precisely detects and chooses target proteins in order to induce therapeutic effects. Target medications are categorized into several groups based on disease causes and molecular foundation, and numerous ways are employed to treat illnesses.
Name
CAS Number
Status
Phase
Disease Model
The mouse disease model refers to the manipulation of the mouse genome through gene editing and other techniques, enabling it to carry a specific disease gene or lack an important gene. This provides an experimental platform for researching the mechanism of disease occurrence, drug development, and treatment efficacy.
Category
Name
MGI
Related Gene
Strain of Origin
Publications
References
Disease literature reviews provide a wide spectrum of research findings and clinical data, giving vital information for our comprehensive understanding of illnesses. By researching this material, we may gain a better understanding of the illness's pathophysiology and treatment strategies, as well as give a scientific foundation for disease prevention and management.
Title
PMID
Journal
Year
IF
Comparison
BioGPT