Rare Disease
Parkinson Disease, Late-Onset (PD)
Alias:
Parkinson Disease
Parkinson's Disease
Parkinson Disease, Susceptibility to
Pd
Late Onset Parkinson's Disease
Late Onset Parkinson Disease
Idiopathic Parkinson Disease
Primary Parkinsonism
Paralysis Agitans
Parkinson's
Park
Parkinson Disease, Late-Onset, Susceptibility to
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Primary Parkinson Disease
Pd - [parkinson Disease]
Parkinson Disease Nos
Parkinson, Nos
Neuronal diseases
Eye diseases
Muscle diseases
Mental diseases
Basic Information
Parkinson Disease, Late-Onset, also known as parkinson disease, is related to hereditary late-onset parkinson disease and parkinson disease 21, and has symptoms including angina pectoris, back pain and headache. An important gene associated with Parkinson Disease, Late-Onset is MAPT (Microtubule Associated Protein Tau), and among its related pathways/superpathways are Maturation of protein E and Parkinson's disease pathway. The drugs Dexmedetomidine and Idebenone have been mentioned in the context of this disorder. Affiliated tissues include Brain and subthalamic nucleus, and related phenotypes are abnormal autonomic nervous system physiology and hallucinations
Basic Information
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Prevalence
Related Gene
Disease Model
Reference
MALACARD
Medical Symptom
Even among those with the same illness, each patient's condition and symptoms are unique. To provide patient-centered medical care, medical professionals must carefully evaluate individual differences between patients. This involves thorough assessment of medical details when diagnosing and developing treatment plans. To achieve personalized and maximally effective care, practitioners refer to the latest research and standards of care to tailor treatment strategies for each patient.
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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
Gene & Mutation
Diseases are frequently associated with anomalies or mutations in certain genes. These genes and mutations can disrupt cellular functioning and induce physiological imbalances, resulting in illnesses. In-depth research on illness genes and mutations can help us better understand disease etiology and give new ideas and approaches for disease prevention, diagnosis, and therapy.
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Gene
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Drugs
Gene target medications are a novel form of treatment that can alter genes or proteins while also blocking disease processes. It precisely detects and chooses target proteins in order to induce therapeutic effects. Target medications are categorized into several groups based on disease causes and molecular foundation, and numerous ways are employed to treat illnesses.
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Disease Model
The mouse disease model refers to the manipulation of the mouse genome through gene editing and other techniques, enabling it to carry a specific disease gene or lack an important gene. This provides an experimental platform for researching the mechanism of disease occurrence, drug development, and treatment efficacy.
Category
Name
MGI
Related Gene
Strain of Origin
Publications
References
Disease literature reviews provide a wide spectrum of research findings and clinical data, giving vital information for our comprehensive understanding of illnesses. By researching this material, we may gain a better understanding of the illness's pathophysiology and treatment strategies, as well as give a scientific foundation for disease prevention and management.
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PMID
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Comparison
BioGPT