Neovascular Glaucoma
Alias:
Glaucoma, Neovascular
Secondary Angle-Closure Glaucoma with Rubeosis
Glaucoma Neovascular
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Neovascular Glaucoma, also known as glaucoma, neovascular, is related to central retinal vein occlusion and retinal vein occlusion, and has symptoms including progressive peripheral vision loss An important gene associated with Neovascular Glaucoma is TGFB2 (Transforming Growth Factor Beta 2), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Bevacizumab and Mitomycins have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial, and related phenotypes are glaucoma and visual loss
Related ID:
MESH:D015355
Basic Information
Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Adult
1-5/10000
21
214
--
Medical Symptom
#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
1
Abnormality of the eye
Glaucoma
Obligate (100%)
Obligate (100%)
2
Abnormality of the eye
Visual loss
Hallmark (90%)
Very frequent (99-80%)
3
Abnormality of the eye
Retinal vein occlusion
Hallmark (90%)
Very frequent (99-80%)
4
Abnormality of the eye
Iris neovascularization
Hallmark (90%)
Very frequent (99-80%)
5
Abnormality of the eye
Abnormal uvea morphology
Frequent (33%)
Frequent (79-30%)
6
Constitutional symptom
Ocular pain
Frequent (33%)
Frequent (79-30%)
7
Abnormality of the eye
Photophobia
Frequent (33%)
Frequent (79-30%)
8
Abnormality of the cardiovascular system
Abnormality of central retinal artery
Frequent (33%)
Frequent (79-30%)
9
Abnormality of the eye
Visual acuity test abnormality
Frequent (33%)
Frequent (79-30%)
10
Abnormality of the eye
Ocular hypertension
Frequent (33%)
Frequent (79-30%)
16 Results, 10 per Page
1
2
Gene & Mutation
#
Gene
Function
Score
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
No data available
Disease Model
Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
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Comparison
Al agent
Sources
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